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Allopurinol Sodium Solution for injection

What is this medicine?

ALLOPURINOL (al oh PURE i nole) reduces the amount of uric acid the body makes during chemotherapy. Too much uric acid in the blood can cause damage to your kidneys.

How should I use this medicine?

The medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • difficulty passing urine

  • loss of appetite

  • redness, blistering, peeling or loosening of the skin, including inside the mouth

  • unusual bleeding or bruising

  • unusually weak or tired

  • vomiting

  • yellowing of the skin or whites of the eyes

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea

  • drowsiness

  • nausea

  • stomach pain

What may interact with this medicine?

Do not take this medicine with the following medication:

  • didanosine, ddI

This medicine may also interact with the following medications:

  • amoxicillin or ampicillin

  • azathioprine

  • certain medicines used to treat gout

  • chlorpropamide

  • cyclosporine

  • diuretics

  • mercaptopurine

  • probenecid

  • sulfinpyrazone

  • warfarin

What if I miss a dose?

This does not apply.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • kidney disease

  • liver disease

  • an unusual or allergic reaction to allopurinol, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast feeding

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

Drink plenty of water while you are taking this medicine. This will help to reduce the risk of getting gout or kidney stones.

Online Medical Reviewer: Louise Akin, RN, BSN
Online Medical Reviewer: Daphne Pierce-Smith, RN, MSN, FNP, CCRC
Date Last Reviewed: 6/23/2009
© 2000-2014 The StayWell Company, LLC. 780 Township Line Road, Yardley, PA 19067. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.
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