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Lorazepam Solution for injection

What is this medicine?

LORAZEPAM (lor A ze pam) is a benzodiazepine. It is used to treat anxiety and certain types of seizures. It is also used to cause sleep before surgery and to block the memory of the procedure.

How should I use this medicine?

This medicine is for injection into a muscle or into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • changes in vision

  • confusion

  • depression

  • mood changes, excitability or aggressive behavior

  • movement difficulty, staggering or jerky movements

  • muscle cramps

  • restlessness

  • weakness or tiredness

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation or diarrhea

  • difficulty sleeping, nightmares

  • dizziness, drowsiness

  • headache

  • nausea, vomiting

What may interact with this medicine?

  • barbiturate medicines for inducing sleep or treating seizures, like phenobarbital

  • clozapine

  • medicines for depression, mental problems or psychiatric disturbances

  • medicines for sleep

  • phenytoin

  • probenecid

  • theophylline

  • valproic acid

What if I miss a dose?

This does not apply.

Where should I keep my medicine?

This medication will be given to you in a hospital or health clinic setting. You will not be given this medicine to take home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • alcohol or drug abuse problem

  • bipolar disorder, depression, psychosis or other mental health condition

  • glaucoma

  • kidney or liver disease

  • lung disease or breathing difficulties

  • myasthenia gravis

  • Parkinson's disease

  • seizures or a history of seizures

  • suicidal thoughts

  • an unusual or allergic reaction to lorazepam, other benzodiazepines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

You may feel dizzy or drowsy for about 6 to 8 hours after an injection of this medicine. Elderly patients may feel these effects more strongly and for a longer time.

Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. To reduce the risk of dizzy and fainting spells, do not stand or sit up quickly, especially if you are an older patient. Alcohol may increase dizziness and drowsiness. Avoid alcoholic drinks.

This medicine can cause loss of recall of recent events. This loss of memory is only temporary.

Do not treat yourself for coughs, colds, pain or allergies without asking your doctor or health care professional for advice. Some ingredients can increase possible side effects.

Online Medical Reviewer: Louise Akin, RN, BSN
Online Medical Reviewer: Daphne Pierce-Smith, RN, MSN, FNP, CCRC
Date Last Reviewed: 6/22/2009
© 2000-2014 The StayWell Company, LLC. 780 Township Line Road, Yardley, PA 19067. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.
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