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Paroxetine Oral capsule

What is this medicine?

PAROXETINE (pa ROX e teen) is used to treat hot flashes due to menopause.

How should I use this medicine?

Take this medicine by mouth once daily at bedtime. Follow the directions on the prescription label. This medicine can be taken with or without food. Take your medicine at regular intervals. Do not take your medicine more often than directed.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • changes in emotions or moods

  • confusion

  • depression

  • feeling faint or lightheaded, falls

  • seizures

  • suicidal thoughts or actions

  • unusual bleeding or bruising

  • unusually weak or tired

  • weakness

Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):

  • change in sex drive or performance

  • fatigue

  • drowsiness

  • headache

  • insomnia

  • nausea/vomiting

  • upset stomach

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • linezolid

  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

  • methylene blue (injected into a vein)

  • pimozide

  • thioridazine

This medicine may also interact with the following medications:

  • alcohol

  • aspirin and aspirin-like medicines

  • atomoxetine

  • certain medicines for depression, anxiety, or psychotic disturbances

  • certain medicines for irregular heart beat like propafenone, flecainide, encainide, and quinidine

  • certain medicines for migraine headache like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan

  • cimetidine

  • digoxin

  • diuretics

  • fentanyl

  • fosamprenavir

  • furazolidone

  • isoniazid

  • lithium

  • medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin

  • medicines for sleep

  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen

  • phenobarbital

  • phenytoin

  • procarbazine

  • rasagiline

  • ritonavir

  • supplements like St. John's wort, kava kava, valerian

  • tamoxifen

  • tramadol

  • tryptophan

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • bleeding disorders

  • glaucoma

  • heart disease

  • kidney disease

  • liver disease

  • low levels of sodium in the blood

  • mania or bipolar disorder

  • seizures

  • suicidal thoughts, plans, or attempt; a previous suicide attempt by you or a family member

  • take MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

  • take medicines that treat or prevent blood clots

  • an unusual or allergic reaction to paroxetine, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Visit your doctor or health care professional for regular checks on your progress.

Patients and their families should watch out for new or worsening thoughts of suicide or depression. Also watch out for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of treatment or after a change in dose, call your health care professional.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Your mouth may get dry. Chewing sugarless gum, sucking hard candy and drinking plenty of water will help. Contact your doctor if the problem does not go away or is severe.

Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not become pregnant while taking this medicine.

Online Medical Reviewer: Louise Akin, RN, BSN
Online Medical Reviewer: Daphne Pierce-Smith, RN, MSN, FNP, CCRC
Date Last Reviewed: 8/19/2013
© 2000-2014 The StayWell Company, LLC. 780 Township Line Road, Yardley, PA 19067. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.
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