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Ampicillin trihydrate Oral capsule

What is this medicine?

AMPICILLIN (am pi SILL in) is a penicillin antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 30 minutes before or 2 hours after food. Do not take with food. Take your medicine at regular intervals. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think you are better. Do not skip doses or stop your medicine early.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • dark urine

  • fever

  • pain or difficulty passing urine

  • pain when swallowing

  • redness, blistering, peeling or loosening of the skin, including inside the mouth

  • seizures

  • unusual bleeding, bruising

  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea

  • dizziness

  • headache

  • loss of appetite

  • nausea, vomiting

  • sore mouth, tongue

  • stomach upset

What may interact with this medicine?

  • allopurinol

  • birth control pills

  • chloroquine

  • methotrexate

  • probenecid

  • some other antibiotics like erythromycin, tetracycline

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • bowel disease, like colitis

  • heart disease

  • kidney disease

  • liver disease

  • seizures disorder

  • an unusual or allergic reaction to ampicillin, other penicillins or antibiotics, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not improve or if you get new symptoms.

Do not treat diarrhea with over the counter products. Contact your doctor if you have diarrhea that lasts more than 2 days or if it is severe and watery.

This medicine can interfere with some urine glucose tests. If you use such tests, talk with your health care professional.

Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control.

Online Medical Reviewer: Louise Akin, RN, BSN
Online Medical Reviewer: Daphne Pierce-Smith, RN, MSN, FNP, CCRC
Date Last Reviewed: 3/10/2009
© 2000-2014 The StayWell Company, LLC. 780 Township Line Road, Yardley, PA 19067. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.
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