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Brompheniramine Maleate, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide Oral syrup

What is this medicine?

BROMPHENIRAMINE; DEXTROMETHORPHAN; PSEUDOEPHEDRINE (brome fen IR a meen; dex troe meth OR fan; soo doe e FED rin) is a histamine blocker, cough suppressant, and a decongestant. It can help relieve cough, runny nose, stuffy nose, sneezing, and itchy or watery eyes. This medicine is used to treat allergy and cold symptoms. This medicine will not treat an infection.

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Use a specially marked spoon or container to measure your medicine. Household spoons are not accurate. Take this medicine with food or milk if it upsets your stomach. Take your doses at regular times. Do not take more medicine than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years old for selected conditions, precautions do apply.

Patients over 60 years old may have a stronger reaction to this medicine and need smaller doses.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • changes in vision

  • fast or irregular heartbeat

  • feeling faint or lightheaded, falls

  • hallucinations

  • high blood pressure

  • seizure

  • trouble passing urine or change in the amount of urine

  • vomiting

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • anxiety

  • diarrhea

  • headache

  • loss of appetite

  • nausea

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

This medicine may also interact with the following medications:

  • any product that contains alcohol

  • any stimulant drug

  • barbiturates

  • mecamylamine

  • medicines for anxiety or sleep

  • medicines for chest pain, heart disease, blood pressure or heart rhythm problems

  • medicines for colds or allergies

  • medicines for depression, anxiety, or psychotic disturbances

  • reserpine

  • some herbal or nutritional supplements

  • some medicines for pain

  • some medicines for Parkinson's disease

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store between 8 and 30 degrees C (46 and 86 degrees F). Protect from heat and light. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • asthma

  • blood vessel disease

  • diabetes

  • difficulty passing urine

  • glaucoma

  • high blood pressure

  • other chronic disease

  • stomach ulcer

  • taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days

  • thyroid disease

  • an unusual or allergic reaction to brompheniramine, dextromethorphan, pseudoephedrine, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not improve or if they get worse. If you have trouble falling asleep at night, take the last dose of the day at least a few hours before bedtime.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. To reduce the risk of dizzy or fainting spells, do not stand or sit up quickly, especially if you are an older patient. Alcohol may increase dizziness and drowsiness. Avoid alcoholic drinks.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

This medicine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye doctor if the problem does not go away or is severe.

Online Medical Reviewer: Louise Akin, RN, BSN
Online Medical Reviewer: Daphne Pierce-Smith, RN, MSN, FNP, CCRC
Date Last Reviewed: 3/19/2009
© 2000-2014 The StayWell Company, LLC. 780 Township Line Road, Yardley, PA 19067. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.
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