Nitroglycerin buccal extended-release tablets

What are nitroglycerin buccal (extended-release) tablets?

NITROGLYCERIN (Nitrogard®) is a type of vasodilator. It relaxes blood vessels, increasing the blood and oxygen supply to your heart. Nitroglycerin buccal tablets help prevent or relieve chest pain (angina). (Buccal means close to the cheek and describes where these tablets are placed). Generic nitroglycerin buccal tablets are not yet available.

What should my health care professional know before I take nitroglycerin?

They need to know if you have any of these conditions:

• anemia

• dizziness or fainting spells when rising from a sitting position

• fever

• glaucoma

• head injury, recent stroke, or bleeding in the brain

• liver disease

• low blood pressure, or low blood volume

• previous heart attack

• overactive thyroid

• stomach or intestinal disease

• an unusual or allergic reaction to nitroglycerin, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I take this medicine?

Place a nitroglycerin buccal tablet under the upper lip against the gum, or between the cheek and the gum.You can use a nitroglycerin buccal tablet 5 to 10 minutes before an event likely to produce chest pain. Follow the directions on the prescription label. Let the tablet dissolve slowly; do not swallow whole.Replace the dose if you accidentally swallow it.Try not to touch the tablet with your tongue, or drink hot liquid, as this will increase the rate at which the tablet dissolves. Do not chew tobacco while a tablet is dissolving.Only use these tablets during waking hours.Do not stop taking except on your prescriber's advice. Do not take your medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose (less than 2 hours), take only that dose. Do not take double or extra doses. Extra doses will not take away chest pain.

What drug(s) may interact with nitroglycerin?

Do not take nitroglycerin if you are taking the following medications:

• sildenafil (Viagra®)

• tadalafil (Cialis®)

• vardenafil (Levitra®)

Nitroglycerin may also interact with the following medications:

• alcohol

• bromocriptine

• hawthorn

• heparin

• medicines for anxiety or sleeping problems, such as diazepam or temazepam

• medicines for colds and breathing difficulties

• medicines for high blood pressure

• medicines for mental depression

• medicines for migraine

• medicines for pain

• procainamide

• quinidine

• water pills

Viagra® (sildenafil), Cialis® (tadalafil), or Levitra® (vardenafil) should not be taken with this medication to avoid severe side effects including very low blood pressure and other complications.

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking nitroglycerin?

Check your heart rate and blood pressure regularly while you are taking nitroglycerin. Ask your prescriber or health care professional what your heart rate and blood pressure should be and when you should contact him or her. Tell your prescriber or health care professional if you feel your medicine is no longer having any effect.

You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how nitroglycerin affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Sit or lie down to prevent falling if you feel dizzy or faint after using nitroglycerin. Try to remain calm; this will help you to feel better faster. If you feel dizzy, take several deep breaths and lie down with your feet propped up, or bend forward with your head resting between your knees. Alcohol can make you more dizzy, increase flushing and rapid heartbeats. Avoid alcoholic drinks.

Do not stop taking nitroglycerin suddenly or your symptoms may get worse. Ask your prescriber or health care professional how to gradually reduce the dose.

What side effects may I notice from taking nitroglycerin?

Side effects that you should report to your prescriber or health care professional as soon as possible:

• bluish discoloration of lips, fingernails, or palms of hands

• blurred vision

• dry mouth

• skin rash

• sweating

• the feeling of extreme pressure in the head

• unusual tiredness or weakness

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

• dizziness or fainting

• flushing of the face or neck

• headache, this is common after a dose, but usually only lasts for a short time

• irregular heartbeat, palpitations

• nausea, vomiting

Where can I keep my medicine?

Keep out of the reach of children, especially if you are not using a child-resistant container.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Keep dry in a tightly sealed container. Heat and moisture can reduce the effectiveness of this medicine. Throw away any unused medicine after the expiration date.

Nitroglycerin injection

What is nitroglycerin injection?

NITROGLYCERIN (Nitro-Bid® IV, Tridil®) is a type of vasodilator. It relaxes blood vessels, increasing the blood and oxygen supply to your heart. Nitroglycerin infusions are used to help relieve the pain associated with angina that does not respond to oral (by mouth) treatment; to control blood pressure; and to help treat congestive heart failure. Generic nitroglycerin injections are available.

What should my health care professional know before I receive nitroglycerin?

They need to know if you have any of these conditions:

• anemia

• dizziness or fainting spells when rising from a sitting position

• fever

• glaucoma

• head injury, recent stroke, or bleeding in the brain

• liver disease

• low blood pressure, or low blood volume

• previous heart attack

• overactive thyroid

• stomach or intestinal disease

• an unusual or allergic reaction to nitroglycerin, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I use this medicine?

Nitroglycerin is for infusion into a vein. Do not take by mouth. It is usually given by a health-care professional in a hospital or clinic setting.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply.

What drug(s) may interact with nitroglycerin?

Do not take nitroglycerin if you are taking the following medications:

• sildenafil (Viagra®)

• tadalafil (Cialis®)

• vardenafil (Levitra®)

Nitroglycerin may also interact with the following medications:•alcohol

• bromocriptine

• hawthorn

• heparin•medicines for anxiety or sleeping problems, such as diazepam or temazepam

• medicines for colds and breathing difficulties

• medicines for high blood pressure

• medicines for mental depression

• medicines for migraine

• medicines for pain

• procainamide

• quinidine

• water pills

Viagra® (sildenafil), Cialis® (tadalafil), or Levitra® (vardenafil) should not be taken with this medication to avoid severe side effects including very low blood pressure and other complications.

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking nitroglycerin?

You may get dizzy; to reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can make you more dizzy, increase flushing and rapid heartbeats. Avoid alcoholic drinks.

What side effects may I notice from receiving nitroglycerin?

Side effects that you should report to your prescriber or health care professional as soon as possible:

• bluish discoloration of lips, fingernails, or palms of hands

• blurred vision

• dry mouth

• skin rash

• sweating

• the feeling of extreme pressure in the head

• unusual tiredness or weakness

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

• dizziness or fainting

• flushing of the face or neck

• headache, this is common after a dose, but usually only lasts for a short time

• irregular heartbeat, palpitations

• nausea, vomiting

Where can I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Heat can reduce the effectiveness of this medicine. Throw away any unused medicine after the expiration date.

Nitroglycerin mouth spray

What is nitroglycerin mouth spray?

NITROGLYCERIN (Nitrolingual®) is a type of vasodilator. It relaxes blood vessels, increasing the blood and oxygen supply to your heart. Nitroglycerin mouth spray is used for immediate relief of chest pain during an angina attack, or to prevent pain before activities that can cause an attack (such as climbing stairs, going outdoors in cold weather, or having sex). Generic nitroglycerin mouth spray is not yet available.

What should my health care professional know before I use nitroglycerin?

They need to know if you have any of these conditions:

• anemia

• dizziness or fainting spells when rising from a sitting position

• fever

• glaucoma

• head injury, recent stroke, or bleeding in the brain

• liver disease

• low blood pressure, or low blood volume

• previous heart attack

• overactive thyroid

• stomach or intestinal disease

• an unusual or allergic reaction to nitroglycerin, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I use this medicine?

Nitroglycerin aerosol spray is only for use in the mouth. Use the nitroglycerin mouth spray at the first sign of an angina attack (chest pain or tightness). You can also use nitroglycerin spray 5 to 10 minutes before an event likely to produce chest pain. Follow the directions on the prescription label.Taking care not to shake the container, remove the plastic cover. Hold the container upright and spray either onto or underneath the tongue. Do not breathe in the spray. After each spray, close your mouth but do not swallow. Your symptoms should improve in 1 to 5 minutes. If you are not better within 5 minutes after taking ONE dose of nitroglycerin, call 9-1-1 immediately to seek emergency medical care. Do not take more than 3 doses of nitroglycerin spray over 15 minutes.

If you take nitroglycerin often to relieve symptoms of angina, your prescriber may provide you with different instructions to manage your symptoms. If symptoms do not go away after following these instructions, it is important to call 9-1-1 immediately. Do not take more than 3 doses of nitroglycerin spray over 15 minutes.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply bacause the spray is used as needed. Do not use double or extra doses. Extra doses will not take away chest pain.

What drug(s) may interact with nitroglycerin?

Do not take nitroglycerin if you are taking the following medications:

• sildenafil (Viagra®)

• tadalafil (Cialis®)

• vardenafil (Levitra®)

Nitroglycerin may also interact with the following medications:

• alcohol

• bromocriptine

• hawthorn

• heparin

• medicines for anxiety or sleeping problems, such as diazepam or temazepam

• medicines for colds and breathing difficulties

• medicines for high blood pressure

• medicines for mental depression

• medicines for migraine

• medicines for pain

• procainamide

• quinidine

• water pills

Viagra® (sildenafil), Cialis® (tadalafil), or Levitra® (vardenafil) should not be taken with this medication to avoid severe side effects including very low blood pressure and other complications.

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking nitroglycerin?

Tell your prescriber or health care professional if you feel your medicine is no longer having any effect.

Keep this medicine with you at all times. Use at the first sign of an angina attack (chest pain or tightness). Sit or lie down to prevent falling if you feel dizzy or faint after using nitroglycerin. Try to remain calm; this will help you to feel better faster. If you feel dizzy, take several deep breaths and lie down with your feet propped up, or bend forward with your head resting between your knees.

If nitroglycerin does make you dizzy, do not drive, use machinery, or do anything that needs mental alertness. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can make you more dizzy, increase flushing and rapid heartbeats. Avoid alcoholic drinks.

What side effects may I notice from using nitroglycerin?

Side effects that you should report to your prescriber or health care professional as soon as possible:

• blurred vision

• dry mouth

• skin rash

• sweating

• the feeling of extreme pressure in the head

• unusual tiredness or weakness

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

• dizziness or fainting

• flushing of the face or neck

• headache, this is common after a dose, but usually only lasts for a short time

• irregular heartbeat, palpitations

• nausea, vomiting

Where can I keep my medicine?

Keep out of the reach of children. Do not puncture, break, or burn the aerosol container.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Heat can reduce the effectiveness of this medicine. Throw away any unused medicine after the expiration date.

Nitroglycerin skin ointment

What is nitroglycerin skin ointment?

NITROGLYCERIN (Nitro-Bid®, Nitrol®) is a type of vasodilator. It relaxes blood vessels, increasing the blood and oxygen supply to your heart. Nitroglycerin skin ointment is used regularly to help reduce the number of angina attacks (chest pains). It is not suitable for immediate relief during an angina attack. Generic nitroglycerin skin ointment is available.

What should my health care professional know before I use nitroglycerin?

They need to know if you have any of these conditions:

• anemia

• dizziness or fainting spells when rising from a sitting position

• fever

• glaucoma

• head injury, recent stroke, or bleeding in the brain

• liver disease

• low blood pressure, or low blood volume

• previous heart attack

• overactive thyroid

• stomach or intestinal disease

• an unusual or allergic reaction to nitroglycerin, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I use this medicine?

Nitroglycerin skin ointment is for external use only. Do not take by mouth. Follow the directions on the prescription label. Use exactly as directed. Use one of the ruled papers that come with the ointment to accurately measure the dose. Using the paper, spread a thin layer of ointment about the size of the paper over a clean, dry area of skin on the upper body where there is little or no hair.Avoid injured, irritated, calloused, or scarred areas. Do not rub the ointment into the skin.Tape the paper in place over the ointment to protect your clothing.You can cover the paper with plastic wrap or a plastic bandage. Try not to get the ointment on your fingers. Wash your hands well after use.Remove the paper and clean the area before applying the next dose.Use a different site each day to prevent skin irritation. Do not stop using except on your prescriber's advice. Do not use your medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, apply the ointment as soon as you can. If it is almost time for your next dose, use only that dose. Do not apply two doses at the same time.

What drug(s) may interact with nitroglycerin?

Do not take nitroglycerin if you are taking the following medications:

• sildenafil (Viagra®)

• tadalafil (Cialis®)

• vardenafil (Levitra®)

Nitroglycerin may also interact with the following medications:

• alcohol

• bromocriptine

• hawthorn

• heparin

• medicines for anxiety or sleeping problems, such as diazepam or temazepam

• medicines for colds and breathing difficulties

• medicines for high blood pressure

• medicines for mental depression

• medicines for migraine

• medicines for pain

• procainamide

• quinidine

• water pills

Viagra® (sildenafil), Cialis® (tadalafil), or Levitra® (vardenafil) should not be taken with this medication to avoid severe side effects including very low blood pressure and other complications.

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking nitroglycerin?

Check your heart rate and blood pressure regularly while you are using nitroglycerin. Ask your prescriber or health care professional what your heart rate and blood pressure should be and when you should contact him or her. Tell your prescriber or health care professional if you feel your medicine is no longer having any effect.

You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how nitroglycerin affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. If you feel dizzy, take several deep breaths and lie down with your feet propped up, or bend forward with your head resting between your knees. Alcohol can make you more dizzy, increase flushing and rapid heartbeats. Avoid alcoholic drinks.

Do not stop using nitroglycerin suddenly or your symptoms may get worse. Ask your prescriber or health care professional how to gradually reduce the dose.

What side effects may I notice from using nitroglycerin?

Side effects that you should report to your prescriber or health care professional as soon as possible:

• bluish discoloration of lips, fingernails, or palms of hands

• blurred vision

• dry mouth

• skin rash, or irritation from the ointment

• sweating

• the feeling of extreme pressure in the head

• unusual tiredness or weakness

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

• dizziness or fainting•flushing of the face or neck

• headache, this is common after a dose, but usually only lasts for a short time

• irregular heartbeat, palpitations

• nausea, vomiting

Where can I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F); do not refrigerate. Heat can reduce the effectiveness of this medicine. Throw away any unused medicine after the expiration date.

Nitroglycerin skin patches

What are nitroglycerin skin patches?

NITROGLYCERIN (Transderm-Nitro®, Nitro-Dur®, Nitrodisc®, Minitran®, Deponit®) is a type of vasodilator. It relaxes blood vessels, increasing the blood and oxygen supply to your heart. Nitroglycerin skin patches are used regularly to help reduce the number of angina attacks (chest pains). They are not suitable for immediate relief during an angina attack. Generic nitroglycerin skin patches are available.

What should my health care professional know before I use nitroglycerin?

They need to know if you have any of these conditions:

• anemia

• dizziness or fainting spells when rising from a sitting position

• fever

• glaucoma

• head injury, recent stroke, or bleeding in the brain

• liver disease

• low blood pressure, or low blood volume

• previous heart attack

• overactive thyroid

• stomach or intestinal disease

• an unusual or allergic reaction to nitroglycerin, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I use this medicine?

Nitroglycerin skin patches are for external use only. Follow the directions on the prescription label. Use exactly as directed. One patch contains a full day's supply of nitroglycerin. It is usually worn for up to to 18 hours a day. Apply the patch to an area on the upper body that is clean, dry and hairless; avoid injured, irritated, calloused, or scarred areas. Use a different site each day to prevent skin irritation. Do not cut or trim the patch. Do not stop using except on your prescriber's advice. Do not use your medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, apply the patch as soon as you can. Do not wear two patches at the same time unless told to by your prescriber or health care professional.

What drug(s) may interact with nitroglycerin?

Do not take nitroglycerin if you are taking the following medications:

• sildenafil (Viagra®)

• tadalafil (Cialis®)

• vardenafil (Levitra®)

Nitroglycerin may also interact with the following medications:

• alcohol

• bromocriptine

• hawthorn

• heparin

• medicines for anxiety or sleeping problems, such as diazepam or temazepam

• medicines for colds and breathing difficulties

• medicines for high blood pressure

• medicines for mental depression

• medicines for migraine

• medicines for pain

• procainamide

• quinidine

• water pills

Viagra® (sildenafil), Cialis® (tadalafil), or Levitra® (vardenafil) should not be taken with this medication to avoid severe side effects including very low blood pressure and other complications.

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking nitroglycerin?

Check your heart rate and blood pressure regularly while you are using nitroglycerin. Ask your prescriber or health care professional what your heart rate and blood pressure should be and when you should contact him or her. Tell your prescriber or health care professional if you feel your medicine is no longer having any effect.

You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how nitroglycerin affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. If you feel dizzy, take several deep breaths and lie down with your feet propped up, or bend forward with your head resting between your knees. Alcohol can make you more dizzy, increase flushing and rapid heartbeats. Avoid alcoholic drinks.

Do not stop using nitroglycerin suddenly or your symptoms may get worse. Ask your prescriber or health care professional how to gradually reduce the dose.

If the patch pulls loose or falls off, fold it in half (sticky side in) and throw away out of the reach of children or pets. Replace with a fresh patch.

Avoid use of microwave ovens that are in bad repair; leaking radiation can heat the patch, causing rare reports of burns or changes in the absorption and action of this medicine.

If you are going to have a MRI procedure, let your MRI technician know about the use of these patches. Some drug patches contain an aluminized backing that can become heated when exposed to MRI and may cause burns. You may need to temporarily remove the patch during the MRI procedure.

What side effects may I notice from using nitroglycerin?

Side effects that you should report to your prescriber or health care professional as soon as possible:

• bluish discoloration of lips, fingernails, or palms of hands

• blurred vision

• dry mouth

• skin rash, or irritation from the skin patch

• sweating

• the feeling of extreme pressure in the head

• unusual tiredness or weakness

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

• dizziness or fainting

• flushing of the face or neck

• headache, this is common after a dose, but usually only lasts for a short time

• irregular heartbeat, palpitations

• nausea, vomiting

Where can I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F); do not refrigerate. Heat can reduce the effectiveness of this medicine. Throw away any unused medicine after the expiration date.

Nitroglycerin sublingual tablets

What are nitroglycerin sublingual (under the tongue) tablets?

NITROGLYCERIN (Nitrostat®) is a type of vasodilator. It relaxes blood vessels, increasing the blood and oxygen supply to your heart. Nitroglycerin sublingual tablets are used to relieve chest pain (angina). They can be used to prevent chest pain before activities that can cause an angina attack (such as climbing stairs, going outdoors in cold weather, or having sex). Generic nitroglycerin sublingual tablets are available.

What should my health care professional know before I take nitroglycerin?

They need to know if you have any of these conditions:

• anemia

• dizziness or fainting spells when rising from a sitting position

• fever

• glaucoma

• head injury, recent stroke, or bleeding in the brain

• liver disease

• low blood pressure, or low blood volume

• previous heart attack

• overactive thyroid

• stomach or intestinal disease

• an unusual or allergic reaction to nitroglycerin, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I take this medicine?

You can take nitroglycerin sublingual tablets as needed. At the first sign of an angina attack (chest pain or tightness) place one tablet under your tongue. You can also use a nitroglycerin sublingual tablet 5 to 10 minutes before an event likely to produce chest pain. Follow the directions on the prescription label. Let the tablet dissolve under the tongue; do not swallow whole. Replace the dose if you accidentally swallow it. It will help if your mouth is not dry. Saliva (fluid) around the tablet will help it to dissolve more quickly. Do not eat, drink, smoke, or chew tobacco while a tablet is dissolving. Your symptoms should improve in 1 to 5 minutes. If you are not better within 5 minutes after taking ONE dose of nitroglycerin, call 9-1-1 immediately to seek emergency medical care. Do not take more than 3 nitroglycerin tablets over 15 minutes.

If you take nitroglycerin often to relieve symptoms of angina, your prescriber may provide you with different instructions to manage your symptoms. If symptoms do not go away after following these instructions, it is important to call 9-1-1 immediately. Do not take more than 3 nitroglycerin tablets over 15 minutes.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply bacause the nitroglycerin sublingual tablets are used as needed. Do not use double or extra doses. Extra doses will not take away chest pain.

What drug(s) may interact with nitroglycerin?

Do not take nitroglycerin if you are taking the following medications:

• sildenafil (Viagra®)

• tadalafil (Cialis®)

• vardenafil (Levitra®)

Nitroglycerin may also interact with the following medications:

• alcohol

• bromocriptine

• hawthorn

• heparin

• medicines for anxiety or sleeping problems, such as diazepam or temazepam

• medicines for colds and breathing difficulties

• medicines for high blood pressure

• medicines for mental depression

• medicines for migraine

• medicines for pain

• procainamide

• quinidine

• water pills

Viagra® (sildenafil), Cialis® (tadalafil), or Levitra® (vardenafil) should not be taken with this medication to avoid severe side effects including very low blood pressure and other complications.

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking nitroglycerin?

Tell your prescriber or health care professional if you feel your medicine is no longer having any effect.

Keep this medicine with you at all times. At the first sign of an angina attack (chest pain or tightness) place a tablet under the tongue. Sit or lie down to prevent falling if you feel dizzy or faint after using nitroglycerin. Try to remain calm; this will help you to feel better faster. If you feel dizzy, take several deep breaths and lie down with your feet propped up, or bend forward with your head resting between your knees.

If nitroglycerin does make you dizzy, do not drive, use machinery, or do anything that needs mental alertness. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can make you more dizzy, increase flushing and rapid heartbeats. Avoid alcoholic drinks.

What side effects may I notice from taking nitroglycerin?

Side effects that you should report to your prescriber or health care professional as soon as possible:

• blurred vision

• dry mouth

• skin rash

• sweating

• the feeling of extreme pressure in the head

• unusual tiredness or weakness

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

• dizziness or fainting

• flushing of the face or neck

• headache, this is common after a dose, but usually only lasts for a short time

• irregular heartbeat, palpitations

• nausea, vomiting

Where can I keep my medicine?

Keep out of the reach of children.

These tablets should be dispensed and stored in the original container; keep tightly closed. Remove the cotton from the bottle before the medicine is required for chest pain. Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Heat and moisture can reduce the effectiveness of this medicine. Throw away any unused medicine after the expiration date.

Make sure to replace sublingual nitroglycerin tablets before the expiration date. Keep the tablets in the original container. Do not leave the tablets in a warm place, like your car.

Nitroglycerin sustained-release tablets or capsules

What are nitroglycerin sustained release tablets or capsules?

NITROGLYCERIN (Nitro-Bid®, Nitroglyn®) is a type of vasodilator. It relaxes blood vessels, increasing the blood and oxygen supply to your heart. Nitroglycerin sustained-release products are taken regularly to help prevent or relieve chest pain (angina). They are not suitable for immediate relief during an angina attack. Generic nitroglycerin sustained-release tablets and capsules are available.

What should my health care professional know before I take nitroglycerin?

They need to know if you have any of these conditions:

• anemia

• dizziness or fainting spells when rising from a sitting position

• fever

• glaucoma

• head injury, recent stroke, or bleeding in the brain

• liver disease

• low blood pressure, or low blood volume

• previous heart attack

• overactive thyroid

• stomach or intestinal disease

• an unusual or allergic reaction to nitroglycerin, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I take this medicine?

Take nitroglycerin sustained-release tablets or capsules by mouth. Follow the directions on the prescription label. Swallow the tablets or capsules whole with a drink of water; do not crush or chew. Take on an empty stomach, at least 30 minutes before or 1 to 2 hours after meals. Take at regular intervals and try to take your doses at the same time each day, following the schedule prescribed by your prescriber or health care professional. Continue to take them even if you feel better. It can take several weeks or longer to see the full effects of this medicine. Do not stop taking except on your prescriber's advice. Do not take your medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose (less than 6 hours), take only that dose. Do not take double or extra doses. Extra doses will not take away chest pain.

What drug(s) may interact with nitroglycerin?

Do not take nitroglycerin if you are taking the following medications:

• sildenafil (Viagra®)

• tadalafil (Cialis®)

• vardenafil (Levitra®)

Nitroglycerin may also interact with the following medications:•alcohol

• bromocriptine

• hawthorn

• heparin•medicines for anxiety or sleeping problems, such as diazepam or temazepam

• medicines for colds and breathing difficulties

• medicines for high blood pressure

• medicines for mental depression

• medicines for migraine

• medicines for pain

• procainamide

• quinidine

• water pills

Viagra® (sildenafil), Cialis® (tadalafil), or Levitra® (vardenafil) should not be taken with this medication to avoid severe side effects including very low blood pressure and other complications.

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking nitroglycerin?

Check your heart rate and blood pressure regularly while you are taking nitroglycerin. Ask your prescriber or health care professional what your heart rate and blood pressure should be and when you should contact him or her. Tell your prescriber or health care professional if you feel your medicine is no longer having any effect.

You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how nitroglycerin affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. If you feel dizzy, take several deep breaths and lie down with your feet propped up, or bend forward with your head resting between your knees. Alcohol can make you more dizzy, increase flushing and rapid heartbeats. Avoid alcoholic drinks.

Do not stop taking nitroglycerin suddenly or your symptoms may get worse. Ask your prescriber or health care professional how to gradually reduce the dose.

What side effects may I notice from taking nitroglycerin?

Side effects that you should report to your prescriber or health care professional as soon as possible:

• bluish discoloration of lips, fingernails, or palms of hands

• blurred vision

• dry mouth

• skin rash

• sweating

• the feeling of extreme pressure in the head

• unusual tiredness or weakness

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

• dizziness or fainting

• flushing of the face or neck

• headache, this is common after a dose, but usually only lasts for a short time

• irregular heartbeat, palpitations

• nausea, vomiting

Where can I keep my medicine?

Keep out of the reach of children, especially if you are not using a child-resistant container.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Keep dry in a tightly sealed container. Heat and moisture can reduce the effectiveness of this medicine. Throw away any unused medicine after the expiration date.